Mitochondrial

Elamipretide (SS-31)

SS-31 / MTP-131 / Forzinity

Peptide length
4 amino acids

Modified tetrapeptide

Evidence availableEvidence for a defined medicine

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A mitochondria-targeted peptide. FDA granted Forzinity accelerated approval in 2025 to improve muscle strength in patients with Barth syndrome weighing at least 30 kg.

Family
Mitochondria-targeted peptide
Research target
Cardiolipin-associated mitochondrial membrane
Molecular form
Modified tetrapeptide

What to know about the research

Accelerated approval used an intermediate clinical endpoint and requires confirmation of benefit. It does not establish broad anti-aging or exercise benefits.

Check the exact compound

Distinguish the regulated elamipretide product from research preparations labeled SS-31 and preserve its modified-residue stereochemistry.

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What supports this entry?

The reference list is available. A statement-by-statement source check has not been completed for this entry.

These are selected references, not a complete review of the literature. Source checks were assisted by AI and have not received independent expert review.

Research stage, study quality and regulatory status answer different questions. A study card does not establish treatment benefit or approval.

No study details have been extracted for this exact entry yet. This does not mean that no studies exist. Open the references and check the exact material.

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