Metabolic

Setmelanotide

Imcivree / RM-493

Peptide length
8 amino acids

Cyclic peptide

Evidence availableEvidence for a defined medicine

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An MC4-receptor agonist used for specific causes of obesity. The 2026 FDA label includes acquired hypothalamic obesity alongside defined genetic conditions.

Family
Melanocortin receptor agonist
Research target
Melanocortin 4 receptor
Molecular form
Cyclic peptide

What to know about the research

Eligibility depends on the exact labeled condition and age group. This is not evidence for general obesity treatment.

Check the exact compound

Distinguish setmelanotide from other melanocortin agonists; shared receptor language does not imply the same clinical indication.

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What supports this entry?

The reference list is available. A statement-by-statement source check has not been completed for this entry.

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Research stage, study quality and regulatory status answer different questions. A study card does not establish treatment benefit or approval.

No study details have been extracted for this exact entry yet. This does not mean that no studies exist. Open the references and check the exact material.

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