Growth axis

Ibutamoren (MK-677)

MK-677 / MK677

Molecular format
Small molecule

Small molecule

Research contextHuman studies exist

Read the linked studies for their methods and limitations.

An orally active nonpeptide ghrelin mimetic studied in randomized human trials of endocrine and body-composition outcomes.

Family
Nonpeptide ghrelin mimetic
Research frame
Ghrelin receptor (GHSR)
Molecular format
Small molecule

Read the evidence

In an older-adult trial, increased fat-free mass did not translate into improved strength or function; glucose and insulin sensitivity also changed.

Resolve the identity

This is a small molecule, so a peptide residue count is not applicable. Distinguish ibutamoren from its salt forms.