KPV
Lys-Pro-Val / Alpha-MSH fragment
- Peptide length
- 3 amino acids
Linear tripeptide
Published sequence
KPVAmino acids are shown with one-letter codes. Check the source for the exact molecular form.
Open the sources to check how the studies were done and what they can support.
A tripeptide derived from the C-terminal region of alpha-MSH, studied in experimental inflammatory bowel disease models.
- Family
- Melanocortin-derived tripeptide
- Research target
- Experimental inflammatory pathways
- Molecular form
- Linear tripeptide
What to know about the research
The cited study used murine colitis models. It does not establish treatment benefit in people with inflammatory bowel disease.
Check the exact compound
The source identifies KPV as alpha-MSH(11–13), a three-residue fragment. Do not transfer its findings to the full-length hormone.
What supports this entry?
3 of 3 summary statements linked to checked source passages.
These are selected references, not a complete review of the literature. Source checks were assisted by AI and have not received independent expert review.
Research stage, study quality and regulatory status answer different questions. A study card does not establish treatment benefit or approval.
Check the overview statementSource checked
A tripeptide derived from the C-terminal region of alpha-MSH, studied in experimental inflammatory bowel disease models.
Abstract: Background, Methods and Results
- Selected primary-source passages checked with AI assistance. Scope cautions are editorial interpretations; this is not a complete literature review.
Check the evidence limitationSource checked
The cited study used murine colitis models. It does not establish treatment benefit in people with inflammatory bowel disease.
Abstract: Background, Methods and Results
- Selected primary-source passages checked with AI assistance. Scope cautions are editorial interpretations; this is not a complete literature review.
Check the identity statementSource checked
The source identifies KPV as alpha-MSH(11–13), a three-residue fragment. Do not transfer its findings to the full-length hormone.
Abstract: Background, Methods and Results
- Selected primary-source passages checked with AI assistance. Scope cautions are editorial interpretations; this is not a complete literature review.
Inside the selected studies
Experiments in two murine colitis models
KPV, alpha-MSH(11–13)
- Who or what was studied
- DSS and CD45RB-high transfer colitis models in mice
- Sample size
- Not established. Not established from the checked abstract; full methods require review.
- Compared with
- Comparative experimental colitis groups; full allocation not extracted
- Duration
- Not established. Not established from the checked abstract; full methods require review.
- Weight recovery, tissue inflammation and myeloperoxidase activity.
- Selected study only; source mapping is not independent study-quality appraisal.
- This setting does not establish human treatment benefit.