Growth axis

CJC-1295 with DAC

CJC-1295 / Drug affinity complex

Peptide length
30 amino acids

Albumin-binding GHRH analog

Evidence availableHuman studies exist

Open the sources to check how the studies were done and what they can support.

A long-acting GHRH analog studied in short randomized trials in healthy adults, with sustained GH and IGF-I responses.

Family
GHRH analog
Research target
GHRH receptor pathway
Molecular form
Albumin-binding GHRH analog

What to know about the research

The reported multi-day pharmacokinetics belong to the DAC molecule. Hormone changes in a short study do not establish long-term clinical benefit.

Check the exact compound

Confirm the drug-affinity complex and conjugation site. This record is separate from modified GRF (1–29) sold as no DAC.

FOLLOW THE EVIDENCE

What supports this entry?

1 of 3 summary statements linked to checked source passages.

These are selected references, not a complete review of the literature. Source checks were assisted by AI and have not received independent expert review.

Research stage, study quality and regulatory status answer different questions. A study card does not establish treatment benefit or approval.

Check the overview statementSource checked

A long-acting GHRH analog studied in short randomized trials in healthy adults, with sustained GH and IGF-I responses.

Supporting sourceProlonged stimulation of growth hormone (GH) and insulin-like growth factor I…

Abstract: Design, Participants, Main outcome measures and Results

  • Short studies of hormone endpoints do not establish long-term clinical benefit.

Inside the selected studies

Human study

Two randomized, double-blind, placebo-controlled ascending-dose trials

Long-acting CJC-1295 with DAC; not the non-DAC record

Who or what was studied
Healthy adults aged 21–61
Sample size
Not established. Not stated in the checked abstract
Compared with
Placebo
Duration
28 and 49 days
What was measured
  • GH and IGF-I concentrations
  • Pharmacokinetic parameters
Keep in mind
  • Short hormone-endpoint studies do not establish long-term benefit or effects of a different molecular form.
Read the study source

PubMed abstract: Design, Participants, Main outcome measures

Source checked · Study quality not independently appraised

The remaining statements still need individual source mapping. Use the original references when checking a claim.

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