Growth axis
ACE-031
ActRIIB-Fc / Soluble activin receptor IIB
- Molecular format
- ActRIIB–Fc fusion protein
ActRIIB–Fc fusion protein
Research contextHuman studies exist
Read the linked studies for their methods and limitations.
An experimental activin-receptor fusion protein studied in Duchenne muscular dystrophy.
- Family
- Ligand-trapping fusion protein
- Research frame
- Myostatin and related activin ligands
- Molecular format
- ActRIIB–Fc fusion protein
Read the evidence
The randomized study was discontinued because of non-muscle adverse events. Changes in muscle-related measures cannot be interpreted without that safety outcome.
Resolve the identity
ACE-031 is a receptor fusion protein, not follistatin or a selective short myostatin peptide.