Metabolic

5-Amino-1MQ

5 amino 1MQ / 5-amino-1-methylquinolinium

Molecular form
Small molecule

Small molecule

Evidence availableMostly cell or animal research

Open the sources to check how the studies were done and what they can support.

A small-molecule NNMT inhibitor investigated in cellular and mouse metabolic research.

Family
NNMT inhibitor
Research target
Nicotinamide N-methyltransferase (NNMT)
Molecular form
Small molecule

What to know about the research

The cited obesity results came from a mouse study of NNMT inhibitors. They do not establish human weight-loss efficacy or a clinical dosing regimen.

Check the exact compound

This is a small molecule, not a peptide. Match 5-amino-1-methylquinolinium to the exact compound tested within the NNMT-inhibitor series.

FOLLOW THE EVIDENCE

What supports this entry?

3 of 3 summary statements linked to checked source passages.

These are selected references, not a complete review of the literature. Source checks were assisted by AI and have not received independent expert review.

Research stage, study quality and regulatory status answer different questions. A study card does not establish treatment benefit or approval.

Check the overview statementSource checked

A small-molecule NNMT inhibitor investigated in cellular and mouse metabolic research.

Supporting sourceNNMT inhibitors in cells and diet-induced obese mice

Full text section 2.9 and Figure 2; indexed source passages checked

  • Selected primary-source passages checked with AI assistance. Scope cautions are editorial interpretations; this is not a complete literature review.
Check the evidence limitationSource checked

The cited obesity results came from a mouse study of NNMT inhibitors. They do not establish human weight-loss efficacy or a clinical dosing regimen.

Scope limitNNMT inhibitors in cells and diet-induced obese mice

Full text section 2.9 and Figure 2; indexed source passages checked

  • Selected primary-source passages checked with AI assistance. Scope cautions are editorial interpretations; this is not a complete literature review.
Check the identity statementSource checked

This is a small molecule, not a peptide. Match 5-amino-1-methylquinolinium to the exact compound tested within the NNMT-inhibitor series.

Supporting sourceNNMT inhibitors in cells and diet-induced obese mice

Full text section 2.9 and Figure 2; indexed source passages checked

  • Selected primary-source passages checked with AI assistance. Scope cautions are editorial interpretations; this is not a complete literature review.

Inside the selected studies

Animal study

Controlled diet-induced obesity experiment

5-amino-1MQ

Who or what was studied
Male C57BL/6 mice on a high-fat diet
Sample size
18
Compared with
Saline vehicle
Duration
11 days
What was measured
  • Body weight, adipose tissue and metabolic measurements.
Keep in mind
  • Selected study only; source mapping is not independent study-quality appraisal.
  • This setting does not establish human treatment benefit.
Read the study source

Full text section 2.9 and Figure 2; indexed source passages checked

Source checked · Study quality not independently appraised

How we prepare and correct these entries

Read the research in context

Keep your 5-Amino-1MQ research together.

Get the compound summary, evidence notes, source links, and a reading checklist in one research pack.

Get my research pack